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SPTA1 抗体

SPTA1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7270517
发货至: 中国
  • 抗原 See all SPTA1 抗体
    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
    适用
    • 24
    • 12
    • 4
    • 1
    • 1
    • 1
    • 1
    宿主
    • 16
    • 9
    克隆类型
    • 14
    • 11
    单克隆
    标记
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPTA1 antibody is un-conjugated
    应用范围
    • 15
    • 10
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    原理
    alpha 1 Spectrin Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human alpha 1 Spectrin
    亚型
    IgG
    Top Product
    Discover our top product SPTA1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
    别名
    SPTA1 (SPTA1 产品)
    别名
    Spna1 antibody, AF093576 antibody, AI451697 antibody, Spna-1 antibody, ha antibody, ihj antibody, nmf4 antibody, sph antibody, EL2 antibody, HPP antibody, HS3 antibody, SPH3 antibody, SPTA antibody, spectrin, alpha, erythrocytic 1 antibody, spectrin alpha, erythrocytic 1 antibody, Spta1 antibody, SPTA1 antibody
    背景
    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia. [provided by RefSeq, Jul 2008],EL2, HPP, HS3, SPH3, SPTA,Blood,Blood_Blood Cell Antigens,Cardiovascular,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Signal Transduction,SPTA1
    分子量
    280kDa
    基因ID
    6708
    UniProt
    P02549
    途径
    Regulation of Actin Filament Polymerization
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