SESN1 抗体
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- 抗原 See all SESN1 抗体
- SESN1 (Sestrin 1 (SESN1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This SESN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- sestrin 1 Rabbit mAb
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Monoclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthesized peptide derived from human sestrin 1
- 亚型
- IgG
- Top Product
- Discover our top product SESN1 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- SESN1 (Sestrin 1 (SESN1))
- 别名
- SESN1 (SESN1 产品)
- 别名
- zgc:91970 antibody, sestrin-1 antibody, SESN1 antibody, XPA26 antibody, pa26 antibody, sest1 antibody, PA26 antibody, SEST1 antibody, 1110002G11Rik antibody, AU044290 antibody, Pa26 antibody, Sest1 antibody, sesn1-A antibody, sestrin 1 antibody, sestrin 1 L homeolog antibody, SESN1 antibody, sesn1 antibody, Sesn1 antibody, sesn1.L antibody
- 背景
- This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],PA26, SEST1,AMPK Signaling Pathway,Cell Biology & Developmental Biology,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Obesity,SESN1
- 分子量
- 70kDa
- 基因ID
- 27244
- UniProt
- Q9Y6P5
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