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SRRT 抗体 (AA 623-872)

SRRT 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7270253
发货至: 中国
  • 抗原 See all SRRT 抗体
    SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
    抗原表位
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 623-872
    适用
    • 25
    • 7
    • 5
    • 1
    宿主
    • 23
    • 2
    • 1
    克隆类型
    • 26
    多克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    This SRRT antibody is un-conjugated
    应用范围
    • 23
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    原理
    SRRT Rabbit pAb
    序列
    DYYNTCEYPN EDEMPNRCGI IHVRGPMPPN RISHGEVLEW QKTFEEKLTP LLSVRESLSE EEAQKMGRKD PEQEVEKFVT SNTQELGKDK WLCPLSGKKF KGPEFVRKHI FNKHAEKIEE VKKEVAFFNN FLTDAKRPAL PEIKPAQPPG PAQSLTPGLP YPHQTPQGLM PYGQPRPPIL GYGAGAVRPA VPTGGPPYPH APYGAGRGNY DAFRGQGGYP GKPRNRMVRG DPRAIVEYRD LDAPDDVDFF
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 623-872 of human SRRT (NP_001122325.1).
    亚型
    IgG
    Top Product
    Discover our top product SRRT Primary Antibody
  • 应用备注
    IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
    别名
    SRRT (SRRT 产品)
    别名
    CG7843 antibody, Dmel\\CG7843 antibody, anon-WO0118547.166 antibody, ars2 antibody, ars2-A antibody, serrate antibody, ARS2 antibody, ASR2 antibody, 2810019G02Rik antibody, ASR2A antibody, ASR2B antibody, ASR2C antibody, ASR2D antibody, Ars2 antibody, Asr2 antibody, MGC92060 antibody, CHUNP6881 antibody, zgc:92060 antibody, Arsenic resistance protein 2 antibody, serrate, RNA effector molecule S homeolog antibody, serrate, RNA effector molecule antibody, serrate RNA effector molecule homolog (Arabidopsis) antibody, Ars2 antibody, srrt.S antibody, SRRT antibody, Srrt antibody, srrt antibody
    背景
    Acts as a mediator between the cap-binding complex (CBC and the primary microRNAs (miRNAs processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi by miRNAs. Binds capped RNAs (m7GpppG-capped RNA, however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity.,SRRT,ARS2,ASR2,serrate,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Drug metabolism,SRRT
    分子量
    96kDa/100kDa
    基因ID
    51593
    UniProt
    Q9BXP5
    途径
    Notch Signaling, Stem Cell Maintenance
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