HsT1196 antibody, SCC antibody, SCCA-1 antibody, SCCA-PD antibody, SCCA1 antibody, T4-A antibody, LEUPIN antibody, PI11 antibody, SCCA-2 antibody, SCCA2 antibody, serpin family B member 3 antibody, serpin family B member 4 antibody, serpin B3 antibody, Somatic cell count antibody, SERPINB3 antibody, SERPINB4 antibody, Serpinb3 antibody, LOC483954 antibody, SCC antibody
背景
Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).,SERPINB3, HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, SSCA1, T4-A, serpin B3,Cell Biology & Developmental Biology,Ubiquitin,SerpinB3