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Selenoprotein S 抗体 (AA 50-150)

SELS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7270197
发货至: 中国
  • 抗原 See all Selenoprotein S (SELS) 抗体
    Selenoprotein S (SELS)
    抗原表位
    • 7
    • 1
    • 1
    • 1
    AA 50-150
    适用
    • 21
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 15
    • 5
    克隆类型
    • 18
    • 3
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Selenoprotein S antibody is un-conjugated
    应用范围
    • 12
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    VIMP Rabbit pAb
    序列
    KLSARLRALR QRQLDRAAAA VEPDVVVKRQ EALAAARLKM QEELNAQVEK HKEKLKQLEE EKRRQKIEMW DSMQEGKSYK GNAKKPQEED SPGPSTSSVL K
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 50-150 of human VIMP (NP_982298.2).
    亚型
    IgG
    Top Product
    Discover our top product SELS Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Selenoprotein S (SELS)
    别名
    SELENOS (SELS 产品)
    别名
    ADO15 antibody, SBBI8 antibody, SELS antibody, SEPS1 antibody, 1500011E07Rik antibody, C78786 antibody, H-4 antibody, H-47 antibody, H4 antibody, H47 antibody, Sels antibody, sg2 antibody, selenoprotein S antibody, SELENOS antibody, Selenos antibody
    背景
    This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER). It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Two additional phylogenetically conserved stem-loop structures (Stem-loop 1 and Stem-loop 2) in the 3' UTR have been shown to function as modulators of Sec insertion in this protein (PMID:23614019). An alternatively spliced transcript variant, lacking the SECIS element and encoding a non-Sec containing shorter isoform, has been described for this gene.,SELENOS,AD-015,ADO15,SBBI8,SELS,SEPS1,VIMP,Signal Transduction,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,SELENOS
    分子量
    21kDa
    基因ID
    55829
    UniProt
    Q9BQE4
    途径
    Cellular Response to Molecule of Bacterial Origin, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
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