This gene encodes a serine/threonine protein kinase that contains a ubiquitin-associated (UBA) domain. The encoded protein is a member of the adenosine monophosphate-activated kinase (AMPK) subfamily of kinases that play a role in conserved signal transduction pathways. A mutation in this gene is associated with early infantile epileptic encephalopathy 30.,SIK1,MSK,SIK,SIK-1,SNF1LK,EIEE30,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centrosome,Cardiovascular,Heart,Cardiogenesis,SIK1