The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008],ROCK-II,Apoptosis,Cancer,Cell Adhesion,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centrosome,Cytoskeleton,Cytoskeleton_Actins,Cytoskeleton_Microtubules,G protein signaling,Kinase,Kinase_Serine/threonine kinases,Signal Transduction,TGF-b-Smad Signaling Pathway,ROCK2