The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,RB1CC1,ATG17,CC1,FIP200,PPP1R131,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Endocrine and metabolic diseases,Diabetes,Regulators,RB1CC1