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RANBP2 抗体

RANBP2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7269843
发货至: 中国
  • 抗原 See all RANBP2 抗体
    RANBP2 (RAN Binding Protein 2 (RANBP2))
    适用
    • 24
    • 19
    • 18
    • 1
    宿主
    • 25
    克隆类型
    • 25
    多克隆
    标记
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    • 3
    • 2
    • 2
    • 1
    • 1
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    • 1
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    This RANBP2 antibody is un-conjugated
    应用范围
    • 13
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    RANBP2 Rabbit pAb
    交叉反应
    小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human RANBP2.
    亚型
    IgG
    Top Product
    Discover our top product RANBP2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    RANBP2 (RAN Binding Protein 2 (RANBP2))
    别名
    RANBP2 (RANBP2 产品)
    别名
    ANE1 antibody, IIAE3 antibody, NUP358 antibody, TRP1 antibody, TRP2 antibody, A430087B05Rik antibody, AI256741 antibody, RGD1560047 antibody, RANBP2 antibody, ane1 antibody, nup358 antibody, trp1 antibody, trp2 antibody, RAN binding protein 2 antibody, E3 SUMO-protein ligase RanBP2 antibody, RANBP2 antibody, Ranbp2 antibody, LOC474539 antibody, ranbp2 antibody, LOC100511376 antibody
    背景
    RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q. [provided by RefSeq, Jul 2008],ADANE, ANE1, IIAE3, NUP358, TRP1, TRP2,Cell Biology & Developmental Biology,Cell Cycle,Epigenetics & Nuclear Signaling,Signal Transduction,Ubiquitin,RANBP2
    基因ID
    5903
    UniProt
    P49792
    途径
    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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