RAB3A 抗体 (AA 100-200)
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- 抗原 See all RAB3A 抗体
- RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))
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抗原表位
- AA 100-200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAB3A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 原理
- RAB3A Rabbit pAb
- 序列
- LMYDITNEES FNAVQDWSTQ IKTYSWDNAQ VLLVGNKCDM EDERVVSSER GRQLADHLGF EFFEASAKDN INVKQTFERL VDVICEKMSE SLDTADPAVT G
- 交叉反应
- 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RAB3A (NP_002857.1).
- 亚型
- IgG
- Top Product
- Discover our top product RAB3A Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))
- 别名
- RAB3A (RAB3A 产品)
- 别名
- RAB3 antibody, rab3a antibody, zgc:92276 antibody, RAB3A antibody, rab-3a antibody, si:ch211-255d18.4 antibody, zgc:112516 antibody, RAB3A, member RAS oncogene family antibody, RAB3A, member RAS oncogene family, a antibody, RAB3A, member RAS oncogene family L homeolog antibody, RAB3A, member RAS oncogene family, b antibody, RAB3A antibody, Rab3a antibody, rab3aa antibody, rab3a.L antibody, rab3a antibody, rab3ab antibody
- 背景
- Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity. Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity. Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By similarity. Stimulates insulin secretion through interaction with RIMS2 or RPH3AL effectors in pancreatic beta cells (By similarity. Regulates calcium-dependent lysosome exocytosis and plasma membrane repair (PMR via the interaction with 2 effectors, SYTL4 and myosin-9/MYH9. Acts as a positive regulator of acrosome content secretion in sperm cells by interacting with RIMS1. Plays also a role in the regulation of dopamine release by interacting with synaptotagmin I/SYT (By similarity. Interacts with MADD (via uDENN domain, the GTP-bound form is preferred for interaction (By similarity.,RAB3A,Signal Transduction,G protein signaling,Signal Transduction,RAB3A
- 分子量
- 24kDa
- 基因ID
- 5864
- UniProt
- P20336
- 途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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