2900054P15Rik antibody, AW555448 antibody, C77700 antibody, RAB12, member RAS oncogene family antibody, RAB12 antibody, Rab12 antibody
背景
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity.,RAB12,Signal Transduction,G protein signaling,Signal Transduction,RAB12