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PDHA1 抗体

PDHA1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7269767
发货至: 中国
  • 抗原 See all PDHA1 抗体
    PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))
    适用
    • 95
    • 56
    • 55
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    • 3
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    • 1
    宿主
    • 88
    • 11
    克隆类型
    • 80
    • 19
    多克隆
    标记
    • 40
    • 6
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    • 3
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    This PDHA1 antibody is un-conjugated
    应用范围
    • 81
    • 36
    • 15
    • 14
    • 14
    • 13
    • 10
    • 10
    • 7
    • 6
    • 3
    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    原理
    PDHA1 Rabbit pAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human PDHA1.
    亚型
    IgG
    Top Product
    Discover our top product PDHA1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:20 - 1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))
    别名
    PDHA1 (PDHA1 产品)
    背景
    The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PDHA1,PDHA,PDHAD,PDHCE1A,PHE1A,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Carbohydrate metabolism,Warburg Effect,PDHA1
    分子量
    40kDa/43kDa/44kDa/47kDa
    基因ID
    5160
    UniProt
    P08559
    途径
    Warburg Effect
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