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PPM1F 抗体 (AA 1-190)

PPM1F 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7269682
发货至: 中国
  • 抗原 See all PPM1F 抗体
    PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
    抗原表位
    • 11
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    AA 1-190
    适用
    • 49
    • 2
    • 1
    宿主
    • 42
    • 7
    克隆类型
    • 45
    • 4
    多克隆
    标记
    • 25
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPM1F antibody is un-conjugated
    应用范围
    • 34
    • 25
    • 20
    • 12
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    PPM1F Rabbit pAb
    序列
    MSSGAPQKSS PMASGAEETP GFLDTLLQDF PALLNPEDPL PWKAPGTVLS QEEVEGELAE LAMGFLGSRK APPPLAAALA HEAVSQLLQT DLSEFRKLPR EEEEEEEDDD EEEKAPVTLL DAQSLAQSFF NRLWEVAGQW QKQVPLAARA SQRQWLVSIH AIRNTRRKME DRHVSLPSFN QLFGLSDPVN
    交叉反应
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PPM1F (NP_055449.1).
    亚型
    IgG
    Top Product
    Discover our top product PPM1F Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
    别名
    PPM1F (PPM1F 产品)
    别名
    1110021B16Rik antibody, 4933427B07Rik antibody, CaMKPase antibody, Popx2 antibody, mKIAA0015 antibody, CAMKP antibody, FEM-2 antibody, POPX2 antibody, hFEM-2 antibody, protein phosphatase, Mg2+/Mn2+ dependent 1F antibody, protein phosphatase 1F (PP2C domain containing) antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1F antibody, PPM1F antibody, Ppm1f antibody
    背景
    The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined.,PPM1F,CAMKP,CaMKPase,FEM-2,POPX2,hFEM-2,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Calcium Signaling,PPM1F
    分子量
    38kDa/49kDa
    基因ID
    9647
    UniProt
    P49593
    途径
    Positive Regulation of Endopeptidase Activity
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