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PKN2 抗体

PKN2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7269646
发货至: 中国
  • 抗原 See all PKN2 抗体
    PKN2 (Protein Kinase N2 (PKN2))
    适用
    • 30
    • 10
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 35
    • 2
    克隆类型
    • 35
    • 2
    单克隆
    标记
    • 24
    • 8
    • 4
    • 1
    This PKN2 antibody is un-conjugated
    应用范围
    • 31
    • 12
    • 11
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    原理
    PRK2/PKN2 Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human PRK2/PRK2/PKN2
    亚型
    IgG
    Top Product
    Discover our top product PKN2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PKN2 (Protein Kinase N2 (PKN2))
    别名
    PKN2 (PKN2 产品)
    别名
    PAK2 antibody, PRK2 antibody, PRKCL2 antibody, PRO2042 antibody, Pak-2 antibody, 6030436C20Rik antibody, AI507382 antibody, Prkcl2 antibody, Stk7 antibody, pak2 antibody, prk2 antibody, pak-2 antibody, pro2042 antibody, PKN2 antibody, si:ch211-83f14.1 antibody, wu:fa97c07 antibody, protein kinase N2 antibody, protein kinase N2 L homeolog antibody, PKN2 antibody, Pkn2 antibody, pkn2.L antibody, pkn2 antibody
    背景
    PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes. Phosphorylates CTTN in hyaluronan-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin. Phosphorylates HDAC5, therefore lead to impair HDAC5 import. Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Stimulates FYN kinase activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation. Regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion. Inhibits Akt pro-survival-induced kinase activity. Mediates Rho protein-induced transcriptional activation via the c-fos serum response factor (SRF. Involved in the negative regulation of ciliogenesis.,PAK2, PRK2, PRKCL2, PRO2042, Pak-2, STK7,Epigenetics & Nuclear Signaling,Kinase,RNA Binding,Signal Transduction,PKN2
    分子量
    112kDa
    基因ID
    5586
    UniProt
    Q16513
    途径
    Cell-Cell Junction Organization
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