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PRR5 抗体 (AA 109-388)

PRR5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7269555
发货至: 中国
  • 抗原 See all PRR5 抗体
    PRR5 (Proline Rich 5 (Renal) (PRR5))
    抗原表位
    • 15
    • 13
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 109-388
    适用
    • 33
    • 18
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 46
    克隆类型
    • 46
    多克隆
    标记
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRR5 antibody is un-conjugated
    应用范围
    • 38
    • 16
    • 13
    • 13
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    原理
    PRR5 Rabbit pAb
    序列
    QKLLDSLAET WDFFFSDVLP MLQAIFYPVQ GKEPSVRQLA LLHFRNAITL SVKLEDALAR AHARVPPAIV QMLLVLQGVH ESRGVTEDYL RLETLVQKVV SPYLGTYGLH SSEGPFTHSC ILEKRLLRRS RSGDVLAKNP VVRSKSYNTP LLNPVQEHEA EGAAAGGTSI RRHSVSEMTS CPEPQGFSDP PGQGPTGTFR SSPAPHSGPC PSRLYPTTQP PEQGLDPTRS SLPRSSPENL VDQILESVDS DSEGIFIDFG RGRGSGMSDL EGSGGRQSVV
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 109-388 of human PRR5 (NP_851850.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PRR5 (Proline Rich 5 (Renal) (PRR5))
    别名
    PRR5 (PRR5 产品)
    别名
    AU043908 antibody, Arhgap8 antibody, C030017C09Rik antibody, C78947 antibody, Protor-1 antibody, Protor1 antibody, FLJ20185k antibody, PP610 antibody, PROTOR-1 antibody, PROTOR1 antibody, pp610 antibody, protor1 antibody, protor2 antibody, proline rich 5 (renal) antibody, proline rich 5 antibody, proline rich 5 L homeolog antibody, Prr5 antibody, PRR5 antibody, prr5.L antibody
    背景
    This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.,PRR5,FLJ20185k,PP610,PROTOR-1,PROTOR1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,PRR5
    分子量
    31kDa/32kDa/41kDa/42kDa/45kDa
    基因ID
    55615
    UniProt
    P85299
    途径
    PI3K-Akt Signaling
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