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PRAME 抗体 (AA 1-200)
PRAME
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
PRAME抗体详情
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抗原
See all PRAME 抗体
PRAME
(Preferentially Expressed Antigen in Melanoma (PRAME))
抗原表位
All epitopes for PRAME 抗体
AA 1-200
适用
All reactivities for PRAME 抗体
人
宿主
All hosts for PRAME 抗体
兔
克隆类型
All clonalities for PRAME 抗体
多克隆
标记
All conjugates for PRAME 抗体
This PRAME antibody is un-conjugated
应用范围
All applications for PRAME 抗体
Western Blotting (WB)
原理
PRAME Rabbit pAb
序列
MERRRLWGSI QSRYISMSVW TSPRRLVELA GQSLLKDEAL AIAALELLPR ELFPPLFMAA FDGRHSQTLK AMVQAWPFTC LPLGVLMKGQ HLHLETFKAV LDGLDVLLAQ EVRPRRWKLQ VLDLRKNSHQ DFWTVWSGNR ASLYSFPEPE AAQPMTKKRK VDGLSTEAEQ PFIPVEVLVD LFLKEGACDE LFSYLIEKVK
交叉反应
人, 小鼠, 大鼠
产品特性
Polyclonal Antibodies
纯化方法
Affinity purification
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PRAME (NP_006106.1).
亚型
IgG
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Discover our top product PRAME Primary Antibody
Alternatives
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使用细节
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应用备注
WB,1:500 - 1:2000
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
PRAME目标详情
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抗原
PRAME
(Preferentially Expressed Antigen in Melanoma (PRAME))
别名
PRAME (PRAME 产品 )
别名
PRAME antibody, CT130 antibody, MAPE antibody, OIP-4 antibody, OIP4 antibody, 4930534P07Rik antibody, preferentially expressed antigen in melanoma antibody, PRAME antibody, Prame antibody
背景
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.,PRAME,CT130,MAPE,OIP-4,OIP4,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Tumor biomarkers,PRAME
分子量
57kDa
基因ID
23532
UniProt
P78395
途径
Retinoic Acid Receptor Signaling Pathway , Nuclear Hormone Receptor Binding
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