PRDM9 抗体
Quick Overview for PRDM9 抗体 (ABIN7269501)
抗原
See all PRDM9 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PRDM9 Rabbit pAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human PRDM9.
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亚型
- IgG
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anti-PR Domain Containing 9 (PRDM9) (Middle Region) antibody
PRDM9 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 9 (PRDM9) (AA 431-480) antibodyPRDM9 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 9 (PRDM9) antibodyPRDM9 适用: 小鼠 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 9 (PRDM9) (AA 440-451) antibodyVerified PRDM9 适用: 大鼠 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PRDM9 (PR Domain Containing 9 (PRDM9))
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别名
- PRDM9
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背景
- The protein encoded by this gene is a zinc finger protein with histone methyltransferase activity that catalyzes histone H3 lysine 4 trimethylation (H3K4me3) during meiotic prophase. This protein contains multiple domains, including a Kruppel-associated box (KRAB) domain, an SSX repression domain (SSXRD), a PRD1-BF1 and RIZ homologous region, a subclass of SET (PR/SET) domain, and a tandem array of C2H2 zinc fingers. The zinc finger array recognizes a short sequence motif, leading to local H3K4me3, and meiotic recombination hotspot activity. The observed allelic variation alters the DNA-binding sequence specificity of the protein, resulting in distinct meiotic recombination hotspots amongst individuals and populations. Multiple alternate alleles of this gene have been described.,PFM6, KMT8B, MSBP3, ZNF899, MEISETZ,PRDM9
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分子量
- 103kDa
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基因ID
- 56979
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UniProt
- Q9NQV7
抗原
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