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PHKA1 抗体 (AA 600-820)

PHKA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7269367
发货至: 中国
  • 抗原 See all PHKA1 抗体
    PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))
    抗原表位
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 600-820
    适用
    • 17
    • 2
    • 2
    • 1
    宿主
    • 16
    • 2
    • 1
    克隆类型
    • 19
    多克隆
    标记
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHKA1 antibody is un-conjugated
    应用范围
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    PHKA1 Rabbit pAb
    序列
    QTGKLSEFLT TSCCTHLSFM DPGPEGKLYS EDYDDNYDYL ESGNWMNDYD STSHARCGDE VARYLDHLLA HTAPHPKLAP TSQKGGLDRF QAAVQTTCDL MSLVTKAKEL HVQNVHMYLP TKLFQASRPS FNLLDSPHPR QENQVPSVRV EIHLPRDQSG EVDFKALVLQ LKETSSLQEQ ADILYMLYTM KGPDWNTELY NERSATVREL LTELYGKVGE I
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 600-820 of human PHKA1 (NP_001116142.1).
    亚型
    IgG
    Top Product
    Discover our top product PHKA1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))
    别名
    PHKA1 (PHKA1 产品)
    别名
    PHKA1 antibody, wu:fl37h01 antibody, 5330411D17 antibody, 9830108K24Rik antibody, Phka antibody, Pcyt1b antibody, PHKA antibody, phosphorylase kinase regulatory subunit alpha 1 antibody, phosphorylase kinase, alpha 1a (muscle) antibody, phosphorylase kinase, alpha 1 (muscle) antibody, phosphorylase kinase alpha 1 antibody, PHKA1 antibody, phka1a antibody, phka1 antibody, Phka1 antibody
    背景
    Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. A pseudogene has been found on chromosome 1.,PHKA1,PHKA,Cancer,Signal Transduction,Kinase,Endocrine & Metabolism,Carbohydrate metabolism,Neuroscience,Calcium Signaling,PHKA1
    分子量
    129kDa/135kDa/137kDa
    基因ID
    5255
    UniProt
    P46020
    途径
    Cellular Glucan Metabolic Process
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