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Phospholamban 抗体 (pSer16, pThr17)

PLN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7269330
发货至: 中国
  • 抗原 See all Phospholamban (PLN) 抗体
    Phospholamban (PLN)
    抗原表位
    • 24
    • 17
    • 11
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    pSer16, pThr17
    适用
    • 79
    • 20
    • 19
    • 3
    • 2
    • 2
    • 2
    宿主
    • 79
    • 1
    • 1
    克隆类型
    • 79
    • 2
    多克隆
    标记
    • 34
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Phospholamban antibody is un-conjugated
    应用范围
    • 34
    • 26
    • 26
    • 25
    • 13
    • 10
    • 9
    • 9
    • 7
    • 6
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB)
    原理
    Phospho-PLN-S16/T17 Rabbit pAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Phosphorylated Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic phosphorylated peptide around of human Phospho-PLN-S16/T17.
    亚型
    IgG
    Top Product
    Discover our top product PLN Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Phospholamban (PLN)
    别名
    PLN (PLN 产品)
    背景
    The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.,CMD1P,CMH18,PLB,PLN,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Calcium Signaling,Cardiovascular,Heart,Contractility,PLN
    分子量
    6kDa
    基因ID
    5350
    UniProt
    P26678
    途径
    Negative Regulation of Transporter Activity
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