CG14816 antibody, DPGAM5 antibody, Dmel\\CG14816 antibody, EG:63B12.4 antibody, PGAM5 antibody, dPGAM5 antibody, BXLBV68 antibody, 2610528A17Rik antibody, RGD1312028 antibody, si:dkey-69p22.1 antibody, wu:fb39f09 antibody, wu:fj34f06 antibody, zgc:112041 antibody, zgc:92057 antibody, Phosphoglycerate mutase 5 antibody, PGAM family member 5, mitochondrial serine/threonine protein phosphatase antibody, phosphoglycerate mutase family member 5 antibody, PGAM family member 5, serine/threonine protein phosphatase, mitochondrial S homeolog antibody, PGAM family member 5, serine/threonine protein phosphatase, mitochondrial antibody, Pgam5 antibody, PGAM5 antibody, pgam5.S antibody, pgam5 antibody
背景
Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.,PGAM5,BXLBV68,Signal Transduction,PGAM5