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- 抗原 See all Patched 1 (PTCH1) 抗体
- Patched 1 (PTCH1)
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抗原表位
- AA 770-970
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Patched 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 原理
- PTCH1 Rabbit pAb
- 序列
- RVRDGLDLTD IVPRETREYD FIAAQFKYFS FYNMYIVTQK ADYPNIQHLL YDLHRSFSNV KYVMLEENKQ LPKMWLHYFR DWLQGLQDAF DSDWETGKIM PNNYKNGSDD GVLAYKLLVQ TGSRDKPIDI SQLTKQRLVD ADGIINPSAF YIYLTAWVSN DPVAYAASQA NIRPHRPEWV HDKADYMPET RLRIPAAEPI E
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 770-970 of human PTCH1 (NP_000255.2).
- 亚型
- IgG
- Top Product
- Discover our top product PTCH1 Primary Antibody
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anti-Patched 1 (PTCH1) (C-Term) antibody
Verified PTCH1 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Patched 1 (PTCH1) antibodyPTCH1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Patched 1 (PTCH1) (AA 1214-1312) antibodyPTCH1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Patched 1 (PTCH1) (AA 213-422) antibodyPTCH1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Patched 1 (PTCH1) antibodyPTCH1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Patched 1 (PTCH1) antibodyPTCH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Patched 1 (PTCH1) (N-Term) antibodyPTCH1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Patched 1 (PTCH1) (Internal Region) antibodyVerified PTCH1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Patched 1 (PTCH1) (C-Term) antibodyPTCH1 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 马, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Patched 1 (PTCH1) (AA 1180-1411) antibodyPTCH1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Patched 1 (PTCH1)
- 别名
- PTCH1 (PTCH1 产品)
- 别名
- BCNS antibody, HPE7 antibody, NBCCS antibody, PTC antibody, PTC1 antibody, PTCH antibody, PTCH11 antibody, lep antibody, ptc1 antibody, ptc2 antibody, Ptch antibody, Ptch2 antibody, Ptc-1 antibody, XPtc1 antibody, patched antibody, patched1 antibody, A230106A15Rik antibody, Ptc antibody, Ptc1 antibody, mes antibody, patched 1 antibody, patched 1 L homeolog antibody, Protein patched homolog 1 antibody, PTCH1 antibody, ptch1 antibody, Ptch1 antibody, ptch1.L antibody, ptc-1 antibody
- 背景
- This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.,PTCH1,BCNS,HPE7,NBCCS,PTC,PTC1,PTCH,PTCH11,patched 1,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Hedgehog Signaling Pathway,Neuroscience,Stem Cells,PTCH1
- 分子量
- 144kDa/153kDa/160kDa/161kDa
- 基因ID
- 5727
- UniProt
- Q13635
- 途径
- Hedgehog Signaling, Carbohydrate Homeostasis, Tube Formation
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