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PAPD5 抗体 (AA 480-590)

PAPD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7269170
发货至: 中国
  • 抗原 See all PAPD5 抗体
    PAPD5 (PAP Associated Domain Containing 5 (PAPD5))
    抗原表位
    • 14
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 480-590
    适用
    • 20
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 19
    • 2
    克隆类型
    • 21
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    This PAPD5 antibody is un-conjugated
    应用范围
    • 19
    • 15
    • 3
    • 1
    Western Blotting (WB)
    原理
    PAPD5 Rabbit pAb
    序列
    YYPNNETESI LGRIIRVTDE VATYRDWISK QWGLKNRPEP SCNGNGVTLI VDTQQLDKCN NNLSEENEAL GKCRSKTSES LSKHSSNSSS GPVSSSSATQ SSSSDVDSDA T
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 480-590 of human PAPD5 (NP_001035374.2).
    亚型
    IgG
    Top Product
    Discover our top product PAPD5 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PAPD5 (PAP Associated Domain Containing 5 (PAPD5))
    别名
    PAPD5 (PAPD5 产品)
    别名
    TRF4-2 antibody, LOC568678 antibody, 5730445M16Rik antibody, 5830428A09 antibody, poly(A) RNA polymerase D5, non-canonical antibody, PAP associated domain containing 5 antibody, PAP associated domain containing 5 L homeolog antibody, PAPD5 antibody, Papd5 antibody, papd5 antibody, CC1G_07969 antibody, papd5.L antibody
    背景
    Terminal nucleotidyltransferase that catalyzes preferentially the transfert of ATP and GTP on RNA 3' poly(A tail creating a heterogeneous 3' poly(A tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation. Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro. Required for cytoplasmic polyadenylation of mRNAs involved in carbohydrate metabolism, including the glucose transporter SLC2A1/GLUT1. Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion. Mediates 3' adenylation of the microRNA MIR21 followed by its 3'-to-5' trimming by the exoribonuclease PARN leading to degradation. Mediates 3' adenylation of H/ACA box snoRNAs (small nucleolar RNAs followed by its 3'-to-5' trimming by the exoribonuclease PARN which enhances snoRNA stability and maturation.,PAPD5,TRF4-2,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Drug resistance,Topoisomerases,PAPD5
    分子量
    41kDa/51kDa/63kDa/64kDa/75kDa
    基因ID
    64282
    UniProt
    Q8NDF8
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