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- 抗原 See all OTUD7B 抗体
- OTUD7B (OTU Domain Containing 7B (OTUD7B))
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抗原表位
- AA 530-700
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OTUD7B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- OTUD7B Rabbit pAb
- 序列
- SKPGGVGTGL GGSSGTETLE KKKKNSLKSW KGGKEEAAGD GPVSEKPPAE SVGNGGSKYS QEVMQSLSIL RTAMQGEGKF IFVGTLKMGH RHQYQEEMIQ RYLSDAEERF LAEQKQKEAE RKIMNGGIGG GPPPAKKPEP DAREEQPTGP PAESRAMAFS TGYPGDFTIP R
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 530-700 of human OTUD7B (NP_064590.2).
- 亚型
- IgG
- Top Product
- Discover our top product OTUD7B Primary Antibody
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anti-OTU Domain Containing 7B (OTUD7B) (AA 759-858) antibody
OTUD7B 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2B4 unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (AA 235-347) antibodyOTUD7B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (C-Term) antibodyOTUD7B 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (Middle Region) antibodyOTUD7B 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (AA 1-427) antibodyOTUD7B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (AA 559-608) antibodyOTUD7B 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (AA 612-661) antibodyOTUD7B 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, Pig, 兔, Bat, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 7B (OTUD7B) (AA 757-784), (C-Term) antibodyOTUD7B 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- OTUD7B (OTU Domain Containing 7B (OTUD7B))
- 别名
- OTUD7B (OTUD7B 产品)
- 别名
- OTUD7B antibody, ZA20D1 antibody, za20d1 antibody, zgc:152772 antibody, cezanne antibody, CEZANNE antibody, 2900060B22Rik antibody, 4930463P07Rik antibody, AI462125 antibody, Trabid2 antibody, Za20d1 antibody, RGD1308111 antibody, OTU deubiquitinase 7B antibody, OTU domain containing 7B antibody, OTUD7B antibody, otud7b antibody, Otud7b antibody
- 背景
- Negative regulator of the non-canonical NF-kappa-B pathway that acts by mediating deubiquitination of TRAF3, an inhibitor of the NF-kappa-B pathway, thereby acting as a negative regulator of B-cell responses. In response to non-canonical NF-kappa-B stimuli, deubiquitinates 'Lys-48'-linked polyubiquitin chains of TRAF3, preventing TRAF3 proteolysis and over-activation of non-canonical NF-kappa-B. Negatively regulates mucosal immunity against infections (By similarity. Deubiquitinates ZAP70, and thereby regulates T cell receptor (TCR signaling that leads to the activation of NF-kappa-B. Plays a role in T cell homeostasis and is required for normal T cell responses, including production of IFNG and IL2 (By similarity. Mediates deubiquitination of EGFR. Has deubiquitinating activity toward 'Lys-11', 'Lys-48' and 'Lys-63'-linked polyubiquitin chains. Has a much higher catalytic rate with 'Lys-11'-linked polyubiquitin chains (in vitro, however the physiological significance of these data are unsure. Hydrolyzes both linear and branched forms of polyubiquitin.,OTUD7B,CEZANNE,ZA20D1,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,OTUD7B
- 分子量
- 88kDa/92kDa
- 基因ID
- 56957
- UniProt
- Q6GQQ9
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