×
我们推荐在您的浏览器上开启Javascript,以获得最佳效果。
NOD2 抗体 (AA 611-910)
NOD2
适用: 人
WB, IHC, IF
宿主: 兔
Polyclonal
unconjugated
NOD2抗体详情
(hide)
抗原
See all NOD2 抗体
NOD2
(Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))
抗原表位
All epitopes for NOD2 抗体
AA 611-910
适用
All reactivities for NOD2 抗体
人
宿主
All hosts for NOD2 抗体
兔
克隆类型
All clonalities for NOD2 抗体
多克隆
标记
All conjugates for NOD2 抗体
This NOD2 antibody is un-conjugated
应用范围
All applications for NOD2 抗体
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
原理
NOD2 Rabbit pAb
序列
AAFYLALSAD VPPALLRHLF NCGRPGNSPM ARLLPTMCIQ ASEGKDSSVA ALLQKAEPHN LQITAAFLAG LLSREHWGLL AECQTSEKAL LRRQACARWC LARSLRKHFH SIPPAAPGEA KSVHAMPGFI WLIRSLYEMQ EERLARKAAR GLNVGHLKLT FCSVGPTECA ALAFVLQHLR RPVALQLDYN SVGDIGVEQL LPCLGVCKAL YLRDNNISDR GICKLIECAL HCEQLQKLAL FNNKLTDGCA HSMAKLLACR QNFLALRLGN NYITAAGAQV LAEGLRGNTS LQFLGFWGNR
交叉反应
人, 小鼠, 大鼠
产品特性
Polyclonal Antibodies
纯化方法
Affinity purification
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 611-910 of human NOD2 (NP_071445.1).
亚型
IgG
Alternatives
(show)
使用细节
(hide)
应用备注
WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
限制
仅限研究用
贮存及处理
(hide)
状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
NOD2目标详情
(hide)
抗原
NOD2
(Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))
别名
NOD2 (NOD2 产品 )
别名
ACUG antibody, BLAU antibody, CARD15 antibody, CD antibody, CLR16.3 antibody, IBD1 antibody, NLRC2 antibody, NOD2B antibody, PSORAS1 antibody, Card15 antibody, F830032C23Rik antibody, Nlrc2 antibody, caspase recruitment domain 15 protein antibody, nucleotide binding oligomerization domain containing 2 antibody, nucleotide-binding oligomerization domain containing 2 antibody, TTHERM_01951320 antibody, NOD2 antibody, Nod2 antibody
背景
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,NOD2,ACUG,BLAU,BLAUS,CARD15,CD,CLR16.3,IBD1,NLRC2,NOD2B,PSORAS1,YAOS,Cell Biology & Developmental Biology,Apoptosis,Caspases,NOD2
分子量
22kDa/112kDa/115kDa
基因ID
64127
UniProt
Q9HC29
途径
Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Toll-Like Receptors Cascades , Inflammasome
Recently viewed
(hide)