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NCAPD2 抗体

NCAPD2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7268948
发货至: 中国
  • 抗原 See all NCAPD2 抗体
    NCAPD2 (Non-SMC Condensin I Complex, Subunit D2 (NCAPD2))
    适用
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    宿主
    • 28
    • 2
    克隆类型
    • 29
    • 1
    单克隆
    标记
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    This NCAPD2 antibody is un-conjugated
    应用范围
    • 23
    • 13
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    • 8
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    • 2
    • 2
    Western Blotting (WB)
    原理
    CNAP1 Rabbit mAb
    交叉反应
    人, 小鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human CNAP1.
    亚型
    IgG
    Top Product
    Discover our top product NCAPD2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NCAPD2 (Non-SMC Condensin I Complex, Subunit D2 (NCAPD2))
    别名
    CNAP1 (NCAPD2 产品)
    背景
    Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.,NCAPD2, CAP-D2, CNAP1, hCAP-D2, condensin complex subunit 1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,CNAP1
    分子量
    150kDa
    基因ID
    9918
    UniProt
    Q15021
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