MBNL1 抗体
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- 抗原 See all MBNL1 抗体
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This MBNL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 原理
- MBNL1 Rabbit mAb
- 交叉反应
- 人
- 产品特性
- Monoclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthesized peptide derived from human MBNL1
- 亚型
- IgG
- Top Product
- Discover our top product MBNL1 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
- 别名
- MBNL1 (MBNL1 产品)
- 背景
- This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015],EXP, MBNL,Epigenetics & Nuclear Signaling,RNA Binding,MBNL1
- 分子量
- 40kDa
- 基因ID
- 4154
- UniProt
- Q9NR56
- 途径
- Ribonucleoprotein Complex Subunit Organization
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