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MOV10 抗体

This anti-MOV10 antibody is a 兔 单克隆 antibody detecting MOV10 in WB. Suitable for 人.
产品编号 ABIN7268678
发货至: 中国

Quick Overview for MOV10 抗体 (ABIN7268678)

抗原

See all MOV10 抗体
MOV10 (Moloney Leukemia Virus 10 (MOV10))

适用

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宿主

  • 23
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克隆类型

  • 21
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单克隆

标记

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This MOV10 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    MOV10 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human MOV10

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MOV10 (Moloney Leukemia Virus 10 (MOV10))

    别名

    MOV10

    背景

    5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs. Required for microRNA (miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC. Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2. Restricts retrotransposition of long interspersed element-1 (LINE-1 in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1. Facilitates LINE-1 uridylation by TUT4 and TUT7. Required for embryonic viability and for normal central nervous system development and function. Plays two critical roles in early brain development: suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol (By similarity. May function as a messenger ribonucleoprotein (mRNP clearance factor. Exhibits antiviral activity against dengue virus (DENV.,fSAP113, gb110,Epigenetics & Nuclear Signaling,RNA Binding,MOV10

    分子量

    114kDa

    基因ID

    4343

    UniProt

    Q9HCE1

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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