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MCM7 抗体

MCM7 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7268544
发货至: 中国
  • 抗原 See all MCM7 抗体
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    适用
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    宿主
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    克隆类型
    • 73
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    单克隆
    标记
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    This MCM7 antibody is un-conjugated
    应用范围
    • 78
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    原理
    MCM7 Rabbit mAb
    交叉反应
    人, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human MCM7
    亚型
    IgG
    Top Product
    Discover our top product MCM7 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    别名
    MCM7 (MCM7 产品)
    背景
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146, PPP1R104,Epigenetics & Nuclear Signaling,MCM7
    分子量
    81kDa
    基因ID
    4176
    UniProt
    P33993
    途径
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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