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- 抗原 See all MAML2 抗体
- MAML2 (Mastermind-Like 2 (MAML2))
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抗原表位
- AA 750-850
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAML2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 原理
- MAML2 Rabbit pAb
- 序列
- NQQLMGKKQT LQRQIMEQKQ QLLLQQQMLA DAEKIAPQDQ INRHLSRPPP DYKDQRRNVG NMQPTAQYSG GSSTISLNSN QALANPVSTH TILTPNSSLL S
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide corresponding to a sequence within amino acids 750-850 of human MAML2 (NP_115803.1).
- 亚型
- IgG
- Top Product
- Discover our top product MAML2 Primary Antibody
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anti-Mastermind-Like 2 (MAML2) antibody
MAML2 适用: 人 WB, IF, IHC, FACS, ISt, StM 宿主: 小鼠 Monoclonal MAML2-1302 unconjugated
anti-Mastermind-Like 2 (MAML2) (AA 347-506) antibodyMAML2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mastermind-Like 2 (MAML2) (AA 796-894) antibodyMAML2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A1 unconjugated
anti-Mastermind-Like 2 (MAML2) (AA 780-814) antibodyMAML2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB52651 unconjugated
anti-Mastermind-Like 2 (MAML2) (AA 169-218) antibodyMAML2 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mastermind-Like 2 (MAML2) (AA 324-373) antibodyMAML2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- MAML2 (Mastermind-Like 2 (MAML2))
- 别名
- MAML2 (MAML2 产品)
- 别名
- 5930431H10 antibody, BC032967 antibody, MAM-3 antibody, MAM2 antibody, MAM3 antibody, MLL-MAML2 antibody, mastermind like 2 (Drosophila) antibody, mastermind-like transcriptional coactivator 2 antibody, mastermind like transcriptional coactivator 2 antibody, Maml2 antibody, MAML2 antibody
- 背景
- The protein encoded by this gene is a member of the Mastermind-like family of proteins. All family members are proline and glutamine-rich, and contain a conserved basic domain that binds the ankyrin repeat domain of the intracellular domain of the Notch receptors (ICN1-4) in their N-terminus, and a transcriptional activation domain in their C-terminus. This protein binds to an extended groove that is formed by the interaction of CBF1, Suppressor of Hairless, LAG-1 (CSL) with ICN, and positively regulates Notch signaling. High levels of expression of this gene have been observed in several B cell-derived lymphomas. Translocations resulting in fusion proteins with both CRTC1 and CRTC3 have been implicated in the development of mucoepidermoid carcinomas, while a translocation event with CXCR4 has been linked with chronic lymphocytic leukemia (CLL). Copy number variation in the polyglutamine tract has been observed.,MAML2,MAM-3,MAM2,MAM3,MLL-MAML2,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Notch Signaling Pathway,Stem Cells,MAML2
- 基因ID
- 84441
- UniProt
- Q8IZL2
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