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MSL1 抗体 (AA 210-300)

MSL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7268383
发货至: 中国
  • 抗原 See all MSL1 抗体
    MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
    抗原表位
    • 8
    • 7
    • 6
    • 6
    • 1
    • 1
    AA 210-300
    适用
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 18
    克隆类型
    • 18
    多克隆
    标记
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    This MSL1 antibody is un-conjugated
    应用范围
    • 17
    • 14
    Western Blotting (WB)
    原理
    MSL1 Rabbit pAb
    序列
    LAVPSWRDHS VEPLRDPNPS DLLENLDDSV FSKRHAKLEL DEKRRKRWDI QRIREQRILQ RLQLRMYKKK GIQESEPEVT SFFPEPDDVE S
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 210-300 of human MSL1 (NP_001012241).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
    别名
    MSL1 (MSL1 产品)
    别名
    MSL-1 antibody, hMSL1 antibody, 2810017F12Rik antibody, 4121402D02Rik antibody, 4930463F05Rik antibody, AA682082 antibody, Msl-1 antibody, male specific lethal 1 homolog antibody, male-specific lethal 1 homolog (Drosophila) antibody, MSL1 antibody, Msl1 antibody
    背景
    Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34' (H2BK34Ub. This modification in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.,MSL-1,hMSL1,MSL1,Epigenetics & Nuclear Signaling,Histones,MSL1
    基因ID
    339287
    UniProt
    Q68DK7
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