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LGMN 抗体

LGMN 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7268208
发货至: 中国
  • 抗原 See all LGMN 抗体
    LGMN (Legumain (LGMN))
    适用
    • 51
    • 25
    • 24
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 45
    • 7
    克隆类型
    • 47
    • 5
    单克隆
    标记
    • 25
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGMN antibody is un-conjugated
    应用范围
    • 43
    • 22
    • 14
    • 8
    • 8
    • 7
    • 2
    • 2
    • 1
    Western Blotting (WB)
    原理
    Legumain (LGMN) Rabbit mAb
    交叉反应
    人, 小鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human Legumain (LGMN) (LGMN)
    亚型
    IgG
    Top Product
    Discover our top product LGMN Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    LGMN (Legumain (LGMN))
    别名
    LGMN (LGMN 产品)
    背景
    This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008],AEP, LGMN1, PRSC1,Cancer,Cell Biology & Developmental Biology,Cytoskeleton,Endocrine & Metabolism,Extracellular Matrix,Extracellular Matrix_Bone,Immunology & Inflammation,Signal Transduction,Ubiquitin,LGMN
    分子量
    36,57kDa
    基因ID
    5641
    UniProt
    Q99538
    途径
    Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
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