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KIF5B 抗体 (AA 650-770)

The 兔 多克隆 anti-KIF5B antibody (ABIN7268136) specifically detects KIF5B in WB, IHC 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7268136
发货至: 中国
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Quick Overview for KIF5B 抗体 (AA 650-770) (ABIN7268136)

抗原

See all KIF5B 抗体
KIF5B (Kinesin Family Member 5B (KIF5B))

适用

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宿主

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克隆类型

  • 34
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多克隆

标记

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This KIF5B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 650-770

    原理

    KIF5B Rabbit pAb

    序列

    LQNVEQKKRQ LEESVDALSE ELVQLRAQEK VHEMEKEHLN KVQTANEVKQ AVEQQIQSHR ETHQKQISSL RDEVEAKAKL ITDLQDQNQK MMLEQERLRV EHEKLKATDQ EKSRKLHELT V

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 650-770 of human KIF5B (NP_004512.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    KIF5B (Kinesin Family Member 5B (KIF5B))

    别名

    KIF5B

    背景

    Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity. Through binding with PLEKHM2 and ARL8B, directs lysosome movement toward microtubule plus ends (Probable. Involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs toward the immune synapse between effector NK lymphocytes and target cells.,KIF5B,HEL-S-61,KINH,KNS,KNS1,UKHC,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,KIF5B

    分子量

    109kDa

    基因ID

    3799

    UniProt

    P33176

    途径

    Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization
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