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IL-10 抗体

IL10 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7267981
发货至: 中国
  • 抗原 See all IL-10 (IL10) 抗体
    IL-10 (IL10) (Interleukin 10 (IL10))
    适用
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    克隆类型
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    单克隆
    标记
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    This IL-10 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF)
    原理
    IL10 Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human IL10
    亚型
    IgG
    Top Product
    Discover our top product IL10 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    IL-10 (IL10) (Interleukin 10 (IL10))
    别名
    IL10 (IL10 产品)
    别名
    CSIF antibody, GVHDS antibody, IL-10 antibody, IL10A antibody, TGIF antibody, Il-10 antibody, IL10X antibody, interleukin 10 antibody, IL10 antibody, Il10 antibody
    背景
    The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011],CSIF, GVHDS, IL-10, IL10A, TGIF,Apoptosis,Cancer,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Cytokines,Cytokines_Interleukins,Growth factors,Immunology & Inflammation,Tumor immunology,IL10
    分子量
    18kDa
    基因ID
    3586
    UniProt
    P22301
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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