This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008],CD119, IFNGR, IMD27A, IMD27B,CDs,Cell Intrinsic Innate Immunity Signaling Pathway,Cytokines,Cytokines_Interferons,Hematopoietic Progenitors,Immunology & Inflammation,Stem Cells,IFNGR1