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Insulin 抗体

INS 适用: 人 IHC, WB, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7267886
发货至: 中国
  • 抗原 See all Insulin (INS) 抗体
    Insulin (INS)
    适用
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    • 111
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    宿主
    • 136
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    克隆类型
    • 142
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    单克隆
    标记
    • 117
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    This Insulin antibody is un-conjugated
    应用范围
    • 80
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    • 52
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    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
    原理
    Insulin Rabbit mAb
    交叉反应
    小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human Insulin
    亚型
    IgG
    Top Product
    Discover our top product INS Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Insulin (INS)
    别名
    INS (INS 产品)
    别名
    IDDM2 antibody, ILPR antibody, IRDN antibody, MODY10 antibody, ins1 antibody, xins antibody, ins1-a antibody, Insulin antibody, AA986540 antibody, Ins-2 antibody, InsII antibody, Mody antibody, Mody4 antibody, proinsulin antibody, zgc:109842 antibody, igf2-A antibody, ins antibody, ins-a antibody, ins-b antibody, insulin antibody, insulin precursor antibody, insulin II antibody, preproinsulin antibody, insulin L homeolog antibody, insulin S homeolog antibody, INS antibody, INS-IGF2 antibody, ins antibody, Ins antibody, PIN antibody, Ins2 antibody, ins.L antibody, ins.S antibody
    背景
    After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],IDDM;IDDM1;IDDM2;ILPR;IRDN;MODY10;INS;Insulin;insulin,AMPK Signaling Pathway,Cancer,Cardiovascular,Cardiovascular diseases,Cardiovascular diseases_Heart disease,Cell Biology & Developmental Biology,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Diabetes,Endocrine and metabolic diseases_Obesity,Growth factors,Heart,Immunology & Inflammation,Neuroscience,NF-kB Signaling Pathway,Signal Transduction,Stem Cells,INS
    分子量
    kDa
    基因ID
    3630
    UniProt
    P01308
    途径
    NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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