HRASLS3 antibody, HREV107 antibody, HRSL3 antibody, AdPLA antibody, H-REV107-1 antibody, HREV107-1 antibody, HREV107-3 antibody, C78643 antibody, Hrasls3 antibody, Hrev107 antibody, MLP-3 antibody, phospholipase A2 group XVI antibody, phospholipase A2, group XVI antibody, PLA2G16 antibody, Pla2g16 antibody
背景
Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1 and A2 (PLA2 activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity. Shows O-acyltransferase activity,catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE, forming N-acylphosphatidylethanolamine (NAPE, which serves as precursor for N-acylethanolamines (NAEs. Exhibits high N-acyltransferase activity and low phospholipase A1/2 activity. Required for complete organelle rupture and degradation that occur during eye lens terminal differentiation, when fiber cells that compose the lens degrade all membrane-bound organelles in order to provide lens with transparency to allow the passage of light. Organelle membrane degradation is probably catalyzed by the phospholipase activity (By similarity.,PLA2G16,AdPLA,H-REV107,H-REV107-1,HRASLS3,HREV107,HREV107-1,HREV107-3,HRSL3,Cancer,Tumor suppressors,PLA2G16