Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004],HOOK2, HK2, protein Hook homolog 2,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,HOOK2