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ChT 抗体 (AA 421-580)

ChT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7267643
发货至: 中国
  • 抗原 See all ChT 抗体
    ChT (High Affinity Choline Transporter (ChT))
    抗原表位
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 421-580
    适用
    • 9
    • 9
    • 9
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 9
    • 8
    克隆类型
    • 9
    • 8
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    This ChT antibody is un-conjugated
    应用范围
    • 8
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    原理
    SLC5A7 Rabbit pAb
    序列
    LLCVLFVKGT NTYGAVAGYV SGLFLRITGG EPYLYLQPLI FYPGYYPDDN GIYNQKFPFK TLAMVTSFLT NICISYLAKY LFESGTLPPK LDVFDAVVAR HSEENMDKTI LVKNENIKLD ELALVKPRQS MTLSSTFTNK EAFLDVDSSP EGSGTEDNLQ
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 421-580 of human SLC5A7 (NP_068587.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ChT (High Affinity Choline Transporter (ChT))
    别名
    SLC5A7 (ChT 产品)
    别名
    CHT antibody, CHT1 antibody, HMN7A antibody, hCHT antibody, Cht1 antibody, solute carrier family 5 member 7 antibody, solute carrier family 5 (choline transporter), member 7 antibody, SLC5A7 antibody, Slc5a7 antibody
    背景
    This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants.,SLC5A7,CHT,CHT1,CMS20,HMN7A,Signal Transduction,Endocrine & Metabolism,Neuroscience,SLC5A7
    分子量
    63kDa
    基因ID
    60482
    UniProt
    Q9GZV3
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