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- 抗原 See all HBEGF 抗体
- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
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抗原表位
- AA 20-160
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HBEGF antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- HB-EGF Rabbit pAb
- 序列
- LVTGESLERL RRGLAAGTSN PDPPTVSTDQ LLPLGGGRDR KVRDLQEADL DLLRVTLSSK PQALATPNKE EHGKRKKKGK GLGKKRDPCL RKYKDFCIHG ECKYVKELRA PSCICHPGYH GERCHGLSLP VENRLYTYDH T
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human HB-EGF (NP_001936.1).
- 亚型
- IgG
- Top Product
- Discover our top product HBEGF Primary Antibody
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anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 51-150) antibody
HBEGF 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 21-160) antibodyHBEGF 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (EGF Like Domain) antibody (Biotin)HBEGF 适用: 人 WB, ELISA, IP, ICC, IF 宿主: 小鼠 Monoclonal 4G10 Biotin
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (Bound), (EGF Like Domain), (Soluble) antibodyHBEGF 适用: 人 WB, ELISA, IP, ICC, IF 宿主: 小鼠 Monoclonal 4G10 unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) antibodyHBEGF 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 21-160) antibodyHBEGF 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (N-Term) antibodyHBEGF 适用: 人, 小鼠, 大鼠, Pig, Cow, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) antibodyHBEGF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) antibodyHBEGF 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
- 别名
- HBEGF (HBEGF 产品)
- 别名
- hbegf antibody, zgc:165443 antibody, HBEGF antibody, zgc:175091 antibody, DTR antibody, DTS antibody, DTSF antibody, HEGFL antibody, Dtr antibody, GFHB antibody, Hb-egf antibody, Hegfl antibody, AW047313 antibody, Dts antibody, HB-EGF antibody, heparin-binding EGF-like growth factor b antibody, heparin binding EGF like growth factor antibody, Heparin-binding EGF-like growth factor antibody, heparin-binding EGF-like growth factor a antibody, heparin-binding EGF-like growth factor antibody, hbegfb antibody, HBEGF antibody, hbegf antibody, hbegfa antibody, Hbegf antibody
- 背景
- Heparin-binding EGF-like growth factor (HB-EGF) is a 12-16 kDa member of the epidermal growth factor (EGF)family. It possesses an EGF-like domain, and a heparin-binding motif. Mature HB-EGF is a soluble peptide thatarises from proteolytic processing of the transmembrane form. Human HB -EGF shows 76 % and 73 % aasequence identity with rat and mouse HB-EGF, respectively. It is required for normal cardiac valve formationand normal heart function, promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation, it is mitogenic for fibroblasts, but not endothelial cells. HB-EGF classified as agroup 2 ErbB ligand based on its ability to activate both the EGF/ErbB1 and ErbB4 receptors. Activityassociated with ErbB4 binding appears to be limited to non -mitogenic actions, while EGFR binding inducesboth mitogenic and non-mitogenic activity.,HBEGF,DTR,DTS,DTSF,HEGFL,Cancer,Invasion and Metastasis,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,EGF,Cardiovascular,Angiogenesis,Angiogenic growth factors,HBEGF
- 分子量
- 23kDa
- 基因ID
- 1839
- UniProt
- Q99075
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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