Glutathione Peroxidase 2 抗体 (AA 100-180)
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- 抗原 See all Glutathione Peroxidase 2 (GPX2) 抗体
- Glutathione Peroxidase 2 (GPX2)
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抗原表位
- AA 100-180
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Glutathione Peroxidase 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- GPX2 Rabbit pAb
- 序列
- TLVQKCEVNG QNEHPVFAYL KDKLPYPYDD PFSLMTDPKL IIWSPVRRSD VAWNFEKFLI GPEGEPFRRY SRTFPTINIE P
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 100-180 of human GPX2 (NP_002074.2).
- 亚型
- IgG
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Glutathione Peroxidase 2 (GPX2)
- 别名
- GPX2 (GPX2 产品)
- 别名
- ATGPX2 antibody, GLUTATHIONE PEROXIDASE antibody, T9H9.9 antibody, T9H9_9 antibody, glutathione peroxidase 2 antibody, GI-GPx antibody, GPRP antibody, GPRP-2 antibody, GPx-2 antibody, GPx-GI antibody, GSHPX-GI antibody, GSHPx-2 antibody, LOC100136264 antibody, GSHPx-GI antibody, GPX-GI antibody, glutathione peroxidase 2 antibody, glutathione peroxidase 1 antibody, GPX2 antibody, gpx1 antibody, Gpx2 antibody, LELG_01052 antibody
- 背景
- The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human), is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.,GPX2;GI-GPx;GPRP;GPRP-2;GPx-2;GPx-GI;GSHPX-GI;GSHPx-2,Cell Biology & Developmental Biology,Endocrine & Metabolism,GPX2
- 分子量
- 21kDa
- 基因ID
- 2877
- UniProt
- P18283
- 途径
- Thyroid Hormone Synthesis
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