GLUD1 抗体
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- 抗原 See all GLUD1 抗体
- GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This GLUD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- GLUD1 Rabbit mAb
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Monoclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthesized peptide derived from human GLUD1
- 亚型
- IgG
- Top Product
- Discover our top product GLUD1 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))
- 别名
- GLUD1 (GLUD1 产品)
- 背景
- This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016],GDH, GDH1, GLUD,Amino acid metabolism,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Signal Transduction,GLUD1
- 分子量
- 50kDa
- 基因ID
- 2746
- UniProt
- P00367
- 途径
- Positive Regulation of Peptide Hormone Secretion, Warburg Effect
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