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GLUD1 抗体

GLUD1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7267411
发货至: 中国
  • 抗原 See all GLUD1 抗体
    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))
    适用
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    宿主
    • 41
    • 9
    • 1
    克隆类型
    • 42
    • 9
    单克隆
    标记
    • 29
    • 7
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    • 2
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    This GLUD1 antibody is un-conjugated
    应用范围
    • 31
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    • 10
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    原理
    GLUD1 Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human GLUD1
    亚型
    IgG
    Top Product
    Discover our top product GLUD1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))
    别名
    GLUD1 (GLUD1 产品)
    背景
    This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016],GDH, GDH1, GLUD,Amino acid metabolism,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Signal Transduction,GLUD1
    分子量
    50kDa
    基因ID
    2746
    UniProt
    P00367
    途径
    Positive Regulation of Peptide Hormone Secretion, Warburg Effect
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