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GNE 抗体

GNE 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7267398
发货至: 中国
  • 抗原 See all GNE 抗体
    GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))
    适用
    • 58
    • 32
    • 18
    宿主
    • 57
    • 1
    克隆类型
    • 58
    单克隆
    标记
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    This GNE antibody is un-conjugated
    应用范围
    • 52
    • 29
    • 18
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    • 13
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    GNE Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of Human GNE.
    亚型
    IgG
    Top Product
    Discover our top product GNE Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))
    别名
    GNE (GNE 产品)
    别名
    DMRV antibody, GLCNE antibody, IBM2 antibody, UAE1 antibody, zgc:77657 antibody, GNE antibody, MGC145505 antibody, NM antibody, Uae1 antibody, 2310066H07Rik antibody, glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase antibody, GNE antibody, gne antibody, Gne antibody
    背景
    The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms.,GNE,DMRV,GLCNE,IBM2,NM,Uae1,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cardiovascular,Blood,GNE
    分子量
    66kDa/71kDa/78kDa/79kDa/83kDa
    基因ID
    10020
    UniProt
    Q9Y223
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