6030440P17Rik antibody, 8430406N05Rik antibody, Gm409 antibody, b2b1562Clo antibody, my antibody, ne antibody, nv1 antibody, RGD1566012 antibody, FRAS1 related extracellular matrix protein 2 antibody, Fras1 related extracellular matrix protein 2 antibody, FREM2 antibody, Frem2 antibody
背景
This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome.,FREM2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Neuroscience,Calcium Signaling,FREM2