BNAR antibody, C9orf143 antibody, C9orf145 antibody, C9orf154 antibody, MOTA antibody, TILRR antibody, TRIGNO2 antibody, RGD1306981 antibody, BC037594 antibody, D430009N09 antibody, D630008K06 antibody, eye antibody, eyes2 antibody, heb antibody, qbrick antibody, FRAS1 related extracellular matrix 1 antibody, Fras1 related extracellular matrix 1 antibody, Fras1 related extracellular matrix protein 1 antibody, FREM1 antibody, Frem1 antibody
背景
This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon, the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.,FREM1,BNAR,C9orf143,C9orf145,C9orf154,MOTA,TILRR,TRIGNO2,Cell Biology & Developmental Biology,FREM1