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FKBP1A 抗体

FKBP1A 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7267211
发货至: 中国
  • 抗原 See all FKBP1A 抗体
    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
    适用
    • 57
    • 28
    • 21
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 56
    • 8
    克隆类型
    • 49
    • 15
    单克隆
    标记
    • 28
    • 9
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This FKBP1A antibody is un-conjugated
    应用范围
    • 34
    • 22
    • 18
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    原理
    FKBP12 Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human FKBP12
    亚型
    IgG
    Top Product
    Discover our top product FKBP1A Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
    别名
    FKBP1A (FKBP1A 产品)
    背景
    The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008],FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_other,Epigenetics & Nuclear Signaling,Immunology & Inflammation,mTOR Signaling Pathway,PI3K-Akt Signaling Pathway,PI3K-Akt Signaling Pathway_Regulator of mTOR complex function,Signal Transduction,TGF-b-Smad Signaling Pathway_Regulator,Translation Control,Translational Control_Regulation of eIF4 and p70 S6 Kinase,FKBP1A
    分子量
    12kDa
    基因ID
    2280
    UniProt
    P62942
    途径
    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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