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FGFR4 抗体

FGFR4 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7267193
发货至: 中国
  • 抗原 See all FGFR4 抗体
    FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
    适用
    • 78
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    宿主
    • 64
    • 16
    克隆类型
    • 62
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    单克隆
    标记
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    This FGFR4 antibody is un-conjugated
    应用范围
    • 45
    • 38
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    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    FGFR4 Rabbit mAb
    交叉反应
    人, 小鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human FGFR4
    亚型
    IgG
    Top Product
    Discover our top product FGFR4 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
    别名
    FGFR4 (FGFR4 产品)
    别名
    FGFR4 antibody, XFGFR-4 antibody, XFGFR-4a antibody, cd334 antibody, fgfr-4 antibody, jtk2 antibody, tkf antibody, xfgfr4 antibody, CD334 antibody, JTK2 antibody, TKF antibody, Fgfr-4 antibody, etID309818.21 antibody, wu:fc13h10 antibody, zgc:111935 antibody, fgfr-4c antibody, fgfr4 antibody, fibroblast growth factor receptor 4 antibody, fibroblast growth factor receptor 4 S homeolog antibody, FGFR4 antibody, fgfr4 antibody, Fgfr4 antibody, fgfr4.S antibody
    背景
    The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. [provided by RefSeq, Jul 2008],CD334, JTK2, TKF,Angiogenesis,Cancer,Cardiovascular,CDs,Cell Biology & Developmental Biology,Cell Type Marker,Cell Type Marker_Neural Stem Cell marker,ESC Pluripotency and Differentiation,Growth factors,Immunology & Inflammation,Kinase,Kinase_Tyrosine kinases,Neural Stem Cells,Neuroscience,Signal Transduction,Stem Cells,FGFR4
    分子量
    88kDa
    基因ID
    2264
    UniProt
    P22455
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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