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- 抗原 See all FEM1A 抗体
- FEM1A (Fem-1 Homolog A (FEM1A))
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抗原表位
- AA 100-300
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FEM1A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- FEM1A Rabbit pAb
- 序列
- RSLLRRGASV NRTTRTNSTP LRAACFDGHL EVVRYLVGEH QADLEVANRH GHTCLMISCY KGHREIARYL LEQGAQVNRR SAKGNTALHD CAESGSLEIL QLLLGCKARM ERDGYGMTPL LAASVTGHTN IVEYLIQEQP GQEQVAGGEA QPGLPQEDPS TSQGCAQPQG APCCSSSPEE PLNGESYESC CPTSREAAVE A
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human FEM1A (NP_061178.1).
- 亚型
- IgG
- Top Product
- Discover our top product FEM1A Primary Antibody
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anti-Fem-1 Homolog A (FEM1A) (AA 1-669) antibody
FEM1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fem-1 Homolog A (FEM1A) (AA 1-669) antibodyFEM1A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fem-1 Homolog A (FEM1A) (C-Term) antibodyVerified FEM1A 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- FEM1A (Fem-1 Homolog A (FEM1A))
- 别名
- FEM1A (FEM1A 产品)
- 别名
- EPRAP antibody, fi20c04 antibody, wu:fi20c04 antibody, zgc:63483 antibody, AW611390 antibody, Fem1aa antibody, fem-1 homolog A antibody, fem-1 homolog a (C. elegans) antibody, feminization 1 homolog a (C. elegans) antibody, FEM1A antibody, Fem1a antibody, fem1a antibody
- 背景
- Substrate-recognition component of a Cul2-RING (CRL2 E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation. The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms. The CRL2(FEM1A complex specifically recognizes proteins with an arginine at the C-terminus: recognizes and binds proteins ending with -Lys/Arg-Xaa-Arg and -Lys/Arg-Xaa-Xaa-Arg C-degrons, such as SIL1 or OR51B2, leading to their ubiquitination and degradation. Promotes ubiquitination and degradation of SLBP. Involved in PGE2-EP4-mediated inhibition of inflammation of macrophages via interaction with NFKB1 and PTGER4 (By similarity. Promotes inflammation in brain microglia through MAP2K4/MKK4-mediated signaling (By similarity.,FEM1A,EPRAP,Cell Biology & Developmental Biology,Apoptosis,Caspases,FEM1A
- 分子量
- 73kDa
- 基因ID
- 55527
- UniProt
- Q9BSK4
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