This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.,EYA3,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Dephosphorylation,Signal Transduction,Stem Cells,Neural Stem Cells,EYA3