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EXOSC7 抗体

EXOSC7 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7267064
发货至: 中国
  • 抗原 See all EXOSC7 抗体
    EXOSC7 (Exosome Component 7 (EXOSC7))
    适用
    • 31
    • 23
    • 8
    • 7
    • 4
    • 4
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    • 3
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    • 2
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    • 1
    宿主
    • 23
    • 8
    克隆类型
    • 25
    • 6
    单克隆
    标记
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This EXOSC7 antibody is un-conjugated
    应用范围
    • 14
    • 13
    • 13
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    EXOSC7 Rabbit mAb
    交叉反应
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human EXOSC7.
    亚型
    IgG
    Top Product
    Discover our top product EXOSC7 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    EXOSC7 (Exosome Component 7 (EXOSC7))
    别名
    EXOSC7 (EXOSC7 产品)
    别名
    EXOSC7 antibody, zgc:110717 antibody, EAP1 antibody, RRP42 antibody, Rrp42p antibody, hRrp42p antibody, p8 antibody, 2610002K22Rik antibody, AV212732 antibody, mKIAA0116 antibody, exosome component 7 antibody, exosome component 7 S homeolog antibody, exosc7 antibody, EXOSC7 antibody, exosc7.S antibody, Exosc7 antibody
    背景
    Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs, and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR and/or Ig variable region somatic hypermutation (SHM by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9 is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.,EXOSC7, EAP1, RRP42, Rrp42p, hRrp42p, p8, exosome component 7,Epigenetics & Nuclear Signaling,EXOSC7
    分子量
    32kDa
    基因ID
    23016
    UniProt
    Q15024
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