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EIF2AK2 抗体 (pThr446)

EIF2AK2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7267028
发货至: 中国
  • 抗原 See all EIF2AK2 抗体
    EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
    抗原表位
    • 48
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    pThr446
    适用
    • 131
    • 76
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    • 2
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    • 1
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    宿主
    • 125
    • 9
    克隆类型
    • 116
    • 18
    单克隆
    标记
    • 69
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    This EIF2AK2 antibody is un-conjugated
    应用范围
    • 103
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    • 9
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    Western Blotting (WB)
    原理
    Phospho-PKR/EIF2AK2-T446 Rabbit mAb
    交叉反应
    产品特性
    Phosphorylated Antibodies
    纯化方法
    Affinity purification
    免疫原
    A phospho specific peptide corresponding to residues surrounding T446 of human PKR/EIF2AK2
    亚型
    IgG
    Top Product
    Discover our top product EIF2AK2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
    别名
    EIF2AK2 (EIF2AK2 产品)
    别名
    PKR antibody, pkr antibody, EIF2AK2 antibody, DKFZp469K1934 antibody, EIF2AK1 antibody, PRKR antibody, 2310047A08Rik antibody, 4732414G15Rik antibody, AI467567 antibody, AI747578 antibody, Pkr antibody, Prkr antibody, Tik antibody, eukaryotic translation initiation factor 2 alpha kinase 2 antibody, eukaryotic translation initiation factor 2-alpha kinase 2 antibody, EIF2AK2 antibody, eif2ak2 antibody, Eif2ak2 antibody
    背景
    The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],EIF2AK1, PKR, PPP1R83, PRKR,Apoptosis,Autophagy,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Protein phosphorylation,Signal Transduction,Translation Control,Translational Control_Regulation of eIF2,EIF2AK2
    分子量
    62kDa
    基因ID
    5610
    UniProt
    P19525
    途径
    DNA Damage Repair, ER-Nucleus Signaling, Hepatitis C
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